PI has developed a device adapter which is part of the official version of micro-manager. The user, therefore, does not need separate modules from the PI product CD but gets it all integrated into micro-manager on delivery.
All PI controllers which can read GCS2 are supported.
The stages can be combined arbitrarily and are supported as "Z stage" (focus) as well as "XY stage" (sample). Any number of stages can be connected; only the active Z drive or XY stage, however, is selected in the user interface.
Further information available here:
PI GCS 2 - Micro-Manager